Griffin is a city in Spalding County, Georgia, United States. The population was 23,451 at the 2000 census. The city is the county seat of Spalding County. Western legend Doc Holliday who fought with Wyatt Earp at the OK Corral, was born and established his dental practice in Griffin before moving west for health reasons. The poet Sydney Lanier was born in Griffin. Both Doc Holliday and Sydney Lanier were baptized in the First Presbyterian Church of Griffin.