Indianapolis is the capital of the U.S. state of Indiana, and the county seat of Marion County, Indiana. The United States Census estimated the city's population, excluding the included towns, at 798,382 in 2008. It is Indiana's largest city and is the 14th largest city in the U.S. , the third largest city in the Midwest, the second most populous state capital, and the most populous state capital east of the Mississippi River. For much of its history, Indianapolis oriented itself around government and industry, particularly manufacturing. Today, Indianapolis has a much more diversified economy, contributing to the fields of education, health care, and finance. Tourism is also a vital part of the economy of Indianapolis, and the city plays host to numerous conventions and sporting events. Of these, perhaps the most well known is the annual Indianapolis 500. Other major sporting events include the Brickyard 400 and the Men's and Women's NCAA Basketball Tournaments. Greater Indianapolis has seen moderate growth among U.S. cities, especially in nearby Hamilton, Hendricks, and Johnson counties. The population of the metropolitan statistical area is estimated at 1,715,459, making it the 33rd-largest in the U.S. The combined statistical area population of Indianapolis is 2,035,327, the 23rd-largest in the U.S.